01Author Guidelines
Thank you for considering the Crystal Journal of Biotechnology,
Bioinformatics & Bioengineering for your research.
Please read these guidelines carefully before submitting
your manuscript. Following the requirements helps the editorial
team assess your work efficiently.
Before preparing your submission
Ensure that your manuscript is relevant to the journal's scope, original, complete and prepared according to these instructions.
02Scope and Article Types
The journal considers the following categories of scholarly contributions:
| Article Type | Description |
| Original Research Article | Full reports presenting original research findings. |
| Review Article | Critical and comprehensive analysis of a research topic. |
| Short Communication | Brief reports of significant preliminary findings. |
| Methods / Software Paper | New tools, algorithms, protocols, software or databases. |
| Case Study / Technical Note | Focused applications, methods or technical advances. |
| Editorial / Perspective | Commissioned or invited scholarly opinion pieces. |
03Before You Submit
- The manuscript is original and is not under consideration by another journal.
- Previously published conference or preprint content is disclosed in the cover letter.
- All authors have approved the final manuscript and agreed to its submission.
- The research complies with relevant ethical standards and applicable approvals.
- The manuscript falls within the scope of CJBBB.
04Manuscript Preparation
Submit manuscripts in Microsoft Word (.docx) format, written in English, double-spaced, with page and line numbers.
Recommended Manuscript Structure
- Title Page: Article title, all authors, affiliations, corresponding author's email and ORCID iDs.
- Abstract: A single paragraph summarising background, methods, results and conclusions.
- Keywords: Four to six relevant keywords.
- Introduction: Background, knowledge gap and research objectives.
- Materials and Methods: Sufficient methodological detail to enable reproducibility.
- Results: Clear presentation of research findings.
- Discussion: Interpretation, limitations and implications.
- Conclusion: Main conclusions and significance.
- Declarations: Ethics approval, consent, funding, conflicts of interest, author contributions and data availability.
- Acknowledgements: Recognition of relevant contributions and support.
- References: Complete and consistently formatted references.
Abstract length
The supplied guideline specifies an abstract limit of up to 250 words. Confirm article-specific word limits with the editorial office.
05Figures, Tables and Supplementary Material
- Submit figures as high-resolution TIFF, PNG or JPG files, minimum 300 dpi.
- Provide clear and informative figure captions.
- Number figures and tables consecutively in order of citation.
- Use SI units and standard gene, protein and species nomenclature.
- Clearly label supplementary files and refer to them in the manuscript.
06Data, Code and Software Availability
Authors are encouraged to deposit sequence data, structures, datasets and code in recognised public repositories.
GenBankBiological sequence data.
SRASequence Read Archive data.
PDBMacromolecular structure data.
GEOGene expression and functional genomics data.
ZenodoResearch datasets and materials.
GitHubSoftware and source-code repositories.
Data availability statement
A data availability statement is required for all articles. Include repository accession numbers or explain the availability of relevant research materials.
07References
- Use one recognised reference style consistently throughout the manuscript.
- Cite all sources appropriately in the main text.
- Ensure every in-text citation has a corresponding reference-list entry.
- Include DOI information wherever available.
Ensure that references are accurate, complete and relevant to the submitted work.
08Research and Publication Ethics
Human and Animal Research
Manuscripts involving human participants should include appropriate ethics committee approval and informed consent information. Animal studies should follow applicable ethical requirements, including relevant ARRIVE guidance.
Authorship
All listed authors should have made a substantial contribution. Changes to the author list after submission require written agreement from all authors.
Plagiarism and Research Integrity
Manuscripts are screened using similarity-detection software. Plagiarism, data fabrication and inappropriate image manipulation are not acceptable.
Conflicts of Interest and Funding
Authors must disclose relevant financial and non-financial interests, as well as funding sources that supported the research.
Use of Artificial Intelligence Tools
AI tools cannot be listed as authors. Any use of AI assistance in writing or analysis must be disclosed. Authors remain fully responsible for the accuracy, originality and integrity of their work.
09Submission Process
1Prepare Your ManuscriptFollow the journal's formatting and ethical requirements.
2Submit OnlineSubmit your manuscript through the official online submission system.
3Include a Cover LetterExplain the significance, originality and relevance of your research.
4Editorial AssessmentThe editorial office checks completeness, scope and basic requirements.
5Peer ReviewEligible manuscripts proceed to double-blind peer review by independent experts.
Official Online Submission Portal
Use the button below to access the submission system. It opens in a separate browser tab.
📤 Open Submission Portal ↗
10Article Processing Charges
The article processing charge supplied for CJBBB is:
Article Processing Charge (APC)
USD 619
Please contact the editorial office for information about payment arrangements, applicable charges and any available waiver provisions before publication.
11Copyright and Licensing
The supplied journal policy identifies the Creative Commons Attribution (CC BY 4.0) licence.
Under the stated policy, authors retain copyright of their work, and readers may access, share and build upon published research with appropriate attribution.
Authors should consult the journal's current copyright and open-access policy for applicable licence terms.
12Peer Review Process
CJBBB is committed to a fair, rigorous and transparent peer-review process. Research articles, reviews and technical papers are evaluated by independent experts before publication.
Type of Review: Double-Blind Peer Review
The identities of authors and reviewers are concealed from one another. Reviewers' identities remain confidential.
Step-by-Step Review Process
1SubmissionThe author submits the manuscript and cover letter through the online submission system.
2Initial Editorial CheckThe editorial office checks scope, formatting, completeness, ethical statements and similarity screening.
3Editor AssignmentThe Editor-in-Chief assigns the manuscript to an Associate Editor or Board Member with relevant expertise.
4Reviewer InvitationAt least two independent experts are invited, considering expertise and potential conflicts of interest.
5Peer ReviewReviewers assess originality, methodology, data quality, validity of conclusions, clarity and ethical compliance.
6Editorial DecisionThe editor considers reviewer reports and reaches an appropriate decision.
7Revision and Re-reviewAuthors submit a revised manuscript and point-by-point response. Revisions may be returned to the original reviewers.
8Acceptance and ProductionAccepted manuscripts proceed through copyediting, typesetting, author proofing and publication.
Possible Editorial Decisions
AcceptAccepted as submitted or subject to minor editorial changes.
Minor RevisionLimited changes are required before acceptance.
Major RevisionSubstantial changes or additional analysis may be required.
RejectThe manuscript does not meet journal standards or scope.
Appeals and Complaints
Authors who believe an editorial decision was unfair may submit a written appeal with a detailed explanation. Appeals are considered by the Editor-in-Chief or an independent editor where a conflict exists. Complaints are handled with reference to COPE guidance.
Ethical Standards in Review
- Reviewers and editors must maintain manuscript confidentiality.
- Conflicts of interest must be declared.
- Editorial decisions should be based on scientific merit.
- Allegations of misconduct are investigated in accordance with journal procedures and relevant publication ethics guidance.
13Reviewer Guidelines
CJBBB values the contribution of independent reviewers in maintaining scholarly quality and research integrity. Reviewers are requested to provide fair, objective, constructive and confidential assessments.
Before Accepting a Review Invitation
- Confirm that the manuscript falls within your area of expertise.
- Ensure that you can complete the review within the requested period.
- Decline if you have a conflict of interest, including recent collaboration, shared affiliation, financial interest or personal relationship with an author.
- Where possible, suggest alternative reviewers if declining.
Confidentiality
Manuscripts are confidential documents. Reviewers must not share, discuss or use manuscript content or data for their own research before publication. Manuscripts must not be forwarded to colleagues without editorial permission. Reviewers should not upload confidential manuscript content to generative AI tools.
What Reviewers Should Evaluate
Originality and SignificanceDoes the research make a meaningful contribution and distinguish itself from existing literature?
Methodology and RigourAre experimental designs, computational methods and statistical analyses appropriate and reproducible?
Results and InterpretationDo the data support the conclusions? Are limitations acknowledged and figures accurate?
PresentationIs the manuscript organised, clearly written and properly referenced?
Ethics and IntegrityAre ethics approvals and consent declared? Are there concerns about plagiarism or data manipulation?
Field-Specific QualityAre datasets, benchmarks, software, controls, replicates and relevant approvals adequately described?
Writing Your Review Report
- Summary: Briefly describe the manuscript and your overall assessment.
- Major Comments: Explain significant concerns about design, analysis or validity.
- Minor Comments: Identify smaller issues involving clarity, references, figures or typographical errors.
- Confidential Comments to the Editor: Include relevant confidential observations where necessary.
- Recommendation: Recommend acceptance, minor revision, major revision or rejection.
Professional reviewer conduct
Be objective, constructive and respectful. Criticise the research and its methodology, not the authors personally.
Reviewer Recognition
Reviewer recognition arrangements and certificates, where applicable, should be confirmed with the editorial office.
Become a Reviewer
Researchers with a doctorate or equivalent experience and a relevant publication record are invited to express their interest in joining the journal's reviewer pool. Please send your CV, research areas and ORCID information to the editorial office.
✉ Express Reviewer Interest ↗
14Questions and Editorial Support
For questions about manuscript submission, editorial decisions, publication ethics, fees or reviewer opportunities, please contact the CJBBB editorial office.
Editorial Office
Crystal Journal of Biotechnology, Bioinformatics & Bioengineering
Email: Biotechnology@cspublishers.com
When enquiring about an existing manuscript, include the manuscript ID and article title to help the editorial office identify your submission.
✉ Email Editorial Office
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